A court in Great Britain ruled that a baby suffering from an incurable disease should continue treatment in a hospital, and not at home, as requested by the parents.
Indi Gregory has mitochondrial disease and doctors at Nottingham Hospital say there is nothing more they can do for her.
Her parents asked to be allowed to take Indi home to Derbyshire.
However, the High Court decided that the baby's treatment should continue in a hospice or hospital.
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A hospice is an institution for the treatment of people suffering from serious and often incurable diseases.
This group includes people who are predicted to live no more than six months and who cannot be cured.
The family will appeal the court's decision, announced the Christian Legal Center, which supports the parents of the sick baby.
In the written judgment, it is stated that it would be "impossible" for the eight-month-old child to be disconnected from life support and to continue treatment in the family with palliative care.
Doctors say the baby is currently "obviously distressed and in pain".
They state that extubation, i.e. disconnection from the apparatus, could in theory be performed anywhere and that its further care would be handled by professionals who would deal with complications and try to mitigate or eliminate them.
Due to possible complications, which are now more difficult due to the length of care, her needs after extubation will be even greater, they add.
Mitochondrial disease prevents cells in the body from producing energy and this condition is incurable.
In October, Judge Justice Peel gave doctors permission to turn off the child's life support, saying the medical evidence was "unique and clear".
Since then, however, the parents have failed to persuade judges at the Court of Appeal in London and judges at the European Court of Human Rights in Strasbourg to overturn the decision.
The judge was told on Tuesday that the parents wanted treatment to stop at home.
However, it was decided that it was in the best interest of the baby to have it done in a hospital, where there is proper professional help and equipment.
"I consider it essential that Indi continues to receive the highest quality clinical treatment in a safe environment, which will not be possible at home," the judge said.
A children's hospital in Rome agreed to treat the baby, but a judge rejected a request to move Indi to Italy.
The family's appeal against the decision of the High Court was rejected, and then a protest was held due to this decision.
The Italian government intervened and granted the baby Italian citizenship.
Giorgio Meloni, the Italian prime minister, promised to do everything to save the baby's life.
Dean Gregory, the child's father, said he was disappointed that the hospital and court systems had rejected the offered help from Italy.
"I'm focused on saving my daughter's life and doing everything in her best interest," Dean told the BBC.
"She deserves a chance. From Italy they are offering to pay for everything, we just need to get her there so it wouldn't cost the hospital or the British government anything,
"Everyone is wondering why they don't let her go, they have nothing to lose," he adds.
He says he is convinced that Indi could be saved if she was allowed to continue treatment in Italy.
Dr Keith Girling, director of Nottingham Hospital, said "this is an extremely challenging time for Indi and her family" and their thoughts are with them.
"Following the court's decision, our priority will remain to provide specialist care appropriate to the baby's condition, supporting her family in every way possible," Grilling added.
Watch the video: Life with Ataxia
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