Optimism enhances the effect of analgesics

A patient's attitude can affect how well a pain medication will work. Patients were asked to report their pain level on a scale of one to one hundred. The medicine was given intravenously, in order to control the subjects' knowledge.
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Ažurirano: 20.02.2011. 12:45h

It has been found that optimism can strengthen their effectiveness in blocking pain, while pessimism can reduce their effect, reports Top News. The researchers used a heat source to induce pain in 22 patients, while at the same time scanning their brains and giving them painkillers.

Patients were asked to report their pain level on a scale of one to one hundred. The medicine was given intravenously, in order to control the subjects' knowledge.

The initial average pain score was 66. The patients were then given a powerful analgesic, remifentanil, without their knowledge, and the pain score was 55.

They were then told that they had received an analgesic and the average score dropped to 39. Then, without changing the dose, the subjects were then told that they would no longer receive pain medication and that they could expect pain, immediately afterwards the average pain score rose again to 64.

So, even though the patients still received remifentanil, they reported the same level of pain as when they received no drug at all.

"That's phenomenal. It is one of the best analgesics we have, and the influence of the brain can simply greatly increase its power, or remove it altogether." , explains Professor Irene Tracey with Oxford.

The professor explains how people with chronic diseases who have unsuccessfully tried to consume various medicines for many years have built up a huge negative experience, which according to this research could affect their future in health care.

"Doctors need more time for consultation and research on the cognitive side of the disease. Essentially the focus is on the physiology, not the mind, and all of that can be a real barrier to healing." Tracey announces.

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