The vaccine from the company Pfizer/Bionter created the strongest immune response of the body to covid-19 of the four vaccines tested as part of a study that showed that people vaccinated with Sinopharm may be the most susceptible to infection, the research results published in the journal Cell Host and Microbe showed.
Scientists compared the body's immune response in people vaccinated with Fajero, Sinopharm, AstraZeneca and Sputnik V, and the study was conducted in July on 196 fully vaccinated people in Mongolia, where all four types of vaccines were used, which is rare, writes Bloomberg.
The level of neutralizing antibodies to SARS-CoV-2 varied widely in each of the four vaccine groups.
A "relatively low" concentration of antibodies resulted from vaccination with Sinopharm and Sputnik V, a medium level of antibody concentration developed in those vaccinated with AstraZeneca, and the highest number of antibodies arose after the injection of the Pfizer vaccine, the study showed.
The Russians say the research is flawed
The causes of the differences in the immune response of the organism after vaccination with the mentioned vaccines are now the subject of intensive research by experts.
It will likely include factors such as the amount of active ingredient in each dose of the vaccine, as well as the interval between the first and second doses, wrote the authors of the study, which involved scientists from Stanford University, the Onom Foundation and the National Center for Zoonotic Diseases in Ulaanbaatar. . The results of the study were published on Thursday.
And variations in the way the vaccine was administered may have played a role in the results obtained.
The Russian Direct Investment Fund (RDIF), which participated in the development of the Russian vaccine and is in charge of its international distribution, claims that the comparison of the effectiveness of the vaccine is flawed given that more time passed between the administration of the Sputnik V dose and the measurement of antibody levels than with other vaccines.
RDIF also points out that people who were vaccinated with Sputnik were on average 10 years older than those who received other vaccines.
The results showed that people vaccinated with Sinopharm, who at the time of the study made up 89.2 percent of vaccinated adults in Mongolia, as well as a smaller number of people vaccinated with Sputnik or AstraZeneca, could be more susceptible to the coronavirus due to pre-existing diseases, the authors said.
They pointed out that in further control of the spread of the covid pandemic in Mongolia and in the world, additional public health interventions will be needed, such as booster doses, but also potentially stronger and more effective types of vaccine.
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