Manchester United had a run of four Premier League triumphs and seemed to have made a habit of winning the small games, but Erik ten Hag's side were brought back to reality.
At "Old Trafford", Fulham rejoiced, they celebrated 2:1 and caused the "red devils" their first defeat in 2024.
It was all in Manchester, and the height of excitement was seen in the final 15 minutes after Harry Maguire equalized in the 89th minute.
Before that, Kalvin Basi checked Andre Onana in the 65th for the well-deserved advantage of the "cottagers", who dominated the first part of the second half.
After Maguire's goal, United went all or nothing and lost.
Adama Traore opened a counterattack in the 97th, went almost 50 meters with the ball at his feet and assisted Alex Iwobi - the offshoot of Arsenal's school was a sure performer for only the second victory of Fulham in the history at the "Theatre of Dreams".
Brighton, with one less player, avoided defeat against Everton thanks to Luis Dunk's goal in the 95th minute, while Aston Villa was better than Nottingham Forest - 4:2.
"Lions" led 3:0 at halftime (Oli Watkins, then Douglas Luiz twice), the visitors reduced it to 3:2 at the beginning of the second half, but they could not do more than that - Lion Bailey secured the victory for Villa.
The first triumph in the Premier League was achieved by Oliver Glasner, the new manager of Crystal Palace.
His team beat Burnley 3:0 at "Selhurst Park", but the resistance of the rival - who played with ten men from the 35th minute - broke only in the middle of the second half.
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